GLRX3 antibody

Catalog No. ABIN7114636

This Rabbit Polyclonal antibody specifically detects GLRX3 in WB, IHC, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for GLRX3 antibody (ABIN7114636)

Target: GLRX3 (Glutaredoxin 3 (GLRX3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLRX3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-GLRX3 Antibody

Purpose: GLRX3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: glutaredoxin 3

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for GLRX3

Target: GLRX3 (Glutaredoxin 3 (GLRX3))

Alternative Name: GLRX3

Background:

Synonyms: Glutaredoxin-3|PKC-interacting cousin of thioredoxin (PICOT)|PKC-theta-interacting protein (PKCq-interacting protein)|Thioredoxin-like protein 2|GLRX3|PICOT|TXNL2

Background: Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator(By similarity). Crucial regulator of cellular iron homeostasis and hemoglobin maturation. May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.

Molecular Weight: 37 kDa

Gene ID: 10539

UniProt: O76003

Pathways: Cell RedoxHomeostasis